Fig. 2: Hepatic and splenic CD11c+DC populations were decreased in BDL-induced liver fibrosis. | Cell Death & Disease

Fig. 2: Hepatic and splenic CD11c+DC populations were decreased in BDL-induced liver fibrosis.

From: Indoleamine 2,3-dioxygenase 1 limits hepatic inflammatory cells recruitment and promotes bile duct ligation-induced liver fibrosis

Fig. 2

A Representative FACS plots (Left) and summary data (right) showing the percentage of hepatic CD11c+DC cells in hepatic NPCs (n ≥ 3). B Representative FACS plots (left) and summary data (Right) showing the percentage of splenic CD11c+DC cells in spleen leukocytes (n = 3). C Immunohistochemistry analysis to detect the expression of CD11c in the livers of sham, BDL-operated mice. The area of CD11c staining was measured using image J software (n = 5–6). D Western blot analysis of the expression of CD11c in the livers of WT control and model mice. In all panels, scale bars, 100 mm. The data are presented as the means ± SEM. P < 0.05 is considered statistically significant. Statistical analysis was analyzed by independent-samples t-test.

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