Fig. 4: The exploration and verification of downstream underlying ZNF280A-induced regulation of LUAD. | Cell Death & Disease

Fig. 4: The exploration and verification of downstream underlying ZNF280A-induced regulation of LUAD.

From: ZNF280A promotes lung adenocarcinoma development by regulating the expression of EIF3C

Fig. 4

A A PrimeView Human Gene Expression Array was performed to identify the differentially expressed genes (DEGs) between shZNF280A and shCtrl groups of NCI-H1299 cells. B, C qPCR B and western blotting C were used to detect the expression of several selected DEGs in NCI-H1299 cells with or without ZNF280A. D A ZNF280A associated interaction network constructed by IPA analysis revealed the potential linkage between ZNF280A and EIF3C. E The expression of EIF3C in LUAD tissues and normal tissues was evaluated by IHC analysis (Scale bar = 100 μm). Data were shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.

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