Fig. 5: EIF3C knockdown inhibited LUAD development in vitro.
From: ZNF280A promotes lung adenocarcinoma development by regulating the expression of EIF3C
A, B Cell models with or without EIF3C knockdown were constructed. The knockdown efficiency of EIF3C in NCI-H1299 cells was assessed by qPCR A and western blotting B, respectively. C Celigo cell counting assay was employed to show the effects of EIF3C on cell proliferation of NCI-H1299 cells. D Colony formation assay was used to evaluate the ability of NCI-H1299 cells with or without EIF3C knockdown to form colonies. E Flow cytometry was performed to detect cell apoptosis of NCI-H1299 cells with or without EIF3C knockdown. F, G The effects of EIF3C on cell migration ability of NCI-H1299 cells were evaluated by wound-healing assay F and Transwell assay (Scale bar = 100 μm) G. The representative images were selected from at least three independent experiments. Data were shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.
