Fig. 1: DHT can inhibit CRPC cell growth.

A–C Cell colony assays were performed to show EnzS-C4-2 (A), EnzS-C4-2B (B), and EnzS-LNCAP (C) and Enzalutamide-resistance (EnzR) cell growth with different concentrations of DHT. D–E Cell counting assay to show cell proliferation in EtOH or 50 nM DHT groups. F–G Cell growth with 50 nM DHT when sh-AR in C4-2 and C4-2B cell line. Data are presented as means ± SD. *p < 0.05 by t-test for two groups or ANOVA for more than two groups.