Fig. 8: NORAD regulated oxaliplatin resistance in vivo. | Cell Death & Disease

Fig. 8: NORAD regulated oxaliplatin resistance in vivo.

From: Oxidative stress activates NORAD expression by H3K27ac and promotes oxaliplatin resistance in gastric cancer by enhancing autophagy flux via targeting the miR-433-3p

Fig. 8

A Xenograft tumors from 10 nude mice’ right flank. SGC-7901 and SGC-7901-R was used to produce the xenograft tumors. B Estimated volumes of xenograft tumors: volume = π/6 × width2 × length (t = 4.383, P = 0.002). C NORAD (t = 14.52, P = 0.001) and miR-433-3p (t = 4.98, P = 0.031) expression in SGC-7901 and SGC-7901-R generated xenograft tumors. D Xenograft tumors from 10 nude mice’ right flank. SGC-7901-R transduced with NORAD knockdown lentivirus and relevant NC cells were used to produce the xenograft tumors. E Estimated volumes of xenograft tumors: volume = π/6 × width2 × length (t = 5.489, P = 0.007).

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