Fig. 6: The role of circFAM114A2 targeting miR-762 in regulating the expression of △NP63 in UCB cells. | Cell Death & Disease

Fig. 6: The role of circFAM114A2 targeting miR-762 in regulating the expression of △NP63 in UCB cells.

From: Circular RNA FAM114A2 suppresses progression of bladder cancer via regulating ∆NP63 by sponging miR-762

Fig. 6

a, b Overexpression of circFAM114A2 could increase the expression of △NP63, while kncokdown of circFAM114A2 displayed contrary effect. c, d miR-762 could suppress the expression level of △NP63, but the effect induced by miR-762 could be eliminated after co-transfection with circFAM114A2. e–g miR-762 could promote migration, invasion, and proliferative ability of UCB cells in vitro, but the effects were attenuated after co-transfection with circFAM114A2. In wound healing assay, scale bars, 100 µm. In transwell assay, scale bars, 50 µm. Date are mean ± SEM, n = 3. ***p < 0.001, **p < 0.01, *p < 0.05 (student’s t test).

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