Fig. 7: Induction of autophagy is critical for the anti-inflammatory actions of IVIG. | Cell Death & Disease

Fig. 7: Induction of autophagy is critical for the anti-inflammatory actions of IVIG.

From: Intravenous immunoglobulin mediates anti-inflammatory effects in peripheral blood mononuclear cells by inducing autophagy

Fig. 7: Induction of autophagy is critical for the anti-inflammatory actions of IVIG.

LPS-stimulated DCs were pretreated with 3MA followed by culture with IVIG (25 mg/ml) for 24 h. Amounts of IL-8, IL-1β and IL-6 (mean ± SEM; n = 7 donors) in the cell-free supernatants were analyzed by ELISA. *P < 0.05; **P < 0.01; ***P < 0.001; as determined by one-way ANOVA with Tukey’s multiple comparison test.

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