Fig. 1: Dysregulation of lnc-Lfar1 in macrophage activation.

a qRT-PCR analysis of the expression of lnc-Lfar1, Ly6c and Il-1β in KCs isolated from mice treated with CCl4 for 0, 1, 2, 4 or 8 weeks. b–g KCs, RAW264.7 and BMMs were stimulated with 20 ng/ml IFN-γ or 100 ng/ml LPS for 24 h and the expression of lnc-Lfar1 and positive control genes (Ly6c, Il-1β, iNos or Mcp-1) was determined by qRT-PCR. *p < 0.05 vs control.