Fig. 2: UHRF1 was required for the mouse spermatogenesis and fertility.
From: UHRF1-repressed 5’-hydroxymethylcytosine is essential for the male meiotic prophase I

a H&E staining of epididymal sections from 12-week-old Uhrf1f/f;Stra8-cre and Uhrf1f/f mice. b Morphology of testes. c The mean testicular weights of the mice from 7 to 36 dpp. d H&E staining of testicular sections at 18, 24, and 36 dpp. e Histology assay showing the testicular tubes in the adult Uhrf1f/f;Stra8-cre and Uhrf1f/f sections. Scale bar, 25 μm. dpp day post-partum. At least three independent experiments were carried out, data are presented as mean ± SEM of three mice in c. ***p ≤ 0.001; **p ≤ 0.01; NS, p > 0.05.