Table. 1 Correlation between PDIA3P1 and clinicopathological characteristics in 608 gliomas.
From: Hypoxia-induced lncRNA PDIA3P1 promotes mesenchymal transition via sponging of miR-124-3p in glioma
Variable | PDIA3P1 high | PDIA3P1 low | p Value | |
|---|---|---|---|---|
Age | >45 | 205 | 111 | <0.001 |
≤45 | 103 | 189 | ||
Gender | Male | 189 | 166 | 0.131 |
Female | 119 | 134 | ||
KPS | ≥80 | 159 | 148 | 0.053 |
<80 | 44 | 24 | ||
WHO grade | II | 77 | 139 | <0.001 |
III | 79 | 158 | ||
IV | 148 | 7 | ||
Transcriptome subtype | Proneural (PN) | 77 | 160 | <0.001 |
Classical (CL) | 71 | 15 | ||
Mesenchymal (MES) | 80 | 17 | ||
IDH status | Wild-type | 191 | 44 | <0.001 |
Mutant | 139 | 286 | ||
1p_19q Codeletion | Non-codeletion | 249 | 243 | 0.349 |
Codeletion | 78 | 90 | ||
MGMT promoter status | Unmethylated | 112 | 49 | <0.001 |
Methylated | 190 | 283 | ||
TERT promoter status | Wild-type | 38 | 124 | <0.001 |
Mutant | 83 | 72 | ||
ATRX status | Wild-type | 281 | 181 | <0.001 |
Mutant | 45 | 149 | ||
ABSOLUTE purity | ≥0.8 | 138 | 110 | 0.049 |
<0.8 | 146 | 163 | ||
ESTIMATE stromal score | ≥600 | 205 | 118 | <0.001 |
<600 | 127 | 213 | ||
ESTIMATE immune score | ≥1000 | 195 | 130 | <0.001 |
<1000 | 137 | 201 |