Table 1 Cdc42 with apical and basal distributions of CRC patients in association with clinicopathologic charcteristics (n = 359).
Characteristic | No. patients, % | Distribution of Cdc42 | P Value | |
|---|---|---|---|---|
Apical, n = 263 (%) | Basal, n = 96 (%) | |||
Gender | 0.181 | |||
Male | 204 (56.8) | 155 (58.9) | 49 (51.0) | |
Female | 155 (43.2) | 108 (41.1) | 47 (49.0) | |
Age(years) | 0.409 | |||
≤67 | 189 (52.6) | 135 (51.3) | 54 (56.3) | |
>67 | 170 (47.4) | 128 (48.7) | 42 (43.7) | |
Location | 0.055 | |||
Colon | 312 (86.9) | 234 (89.0) | 78 (81.3) | |
Rectum | 47 (13.1) | 29 (11.0) | 18 (18.7) | |
Differentiation | 0.325 | |||
Well | 92 (25.6) | 71 (27.0) | 21 (21.9) | |
Moderate | 267 (74.4) | 192 (73.0) | 75 (78.1) | |
AJCC cancer stage | 0.226 | |||
I | 39 (10.9) | 33 (12.6) | 6 (6.3) | |
II | 195 (54.3) | 138 (52.5) | 57 (59.4) | |
III | 116 (32.3) | 84 (31.9) | 32 (33.3) | |
IV | 9 (2.5) | 8 (3.0) | 1 (1.0) | |
LN metastasis | 0.787 | |||
Negative | 247 (68.8) | 182 (69.2) | 65 (67.7) | |
Positive | 112 (31.2) | 81 (30.8) | 31 (32.3) | |
Dis. metastasis | 0.000 | |||
Negative | 329 (91.6) | 250 (95.1) | 79 (82.3) | |
Positive | 30 (8.4) | 13 (4.9) | 17 (17.7) | |
Status | 0.001 | |||
Censored | 204 (56.8) | 163 (62.0) | 41 (42.7) | |
Death | 155 (43.2) | 100 (38.0) | 55 (57.3) | |
