Table 6 Adverse events to CAR-T and treatments for CRS.
Items | Patients (n (%)) |
|---|---|
CRS | 38 (97.4) |
Grade I | 20 (51.3) |
Grade II | 3 (7.7) |
Grade III | 6 (15.4) |
Grade IV | 8 (20.5) |
Grade V | 1 (2.6) |
Symptoms of CRS | |
Fever | 28 (71.8) |
Hypotension | 20 (51.3) |
Hypoxemia | 11 (28.2) |
Capillary leak syndrome | 12 (30.8) |
Hepatic injury | 21 (53.8) |
A | 12 (30.8) |
B | 5 (12.8) |
C | 4 (10.3) |
Heart injury | 5 (12.8) |
I | 4 (10.3) |
IV | 1 (2.6) |
Hematologic toxicities grade | |
I | 2 (5.1) |
II | 3 (7.7) |
III | 7 (17.9) |
IV | 27 (69.2) |
Neurotoxicity | 11 (28.2) |
Infection | 15 (38.5) |
Admission for ICU | 4 (10.3) |
Treatments for CRS | |
Glucocorticoids | 12 (30.8) |
Tocilizumab injection | 15 (38.5) |
