Fig. 5: miRNA-107 reversed the effects of HOTAIRM1 overexpression. | Cell Death & Disease

Fig. 5: miRNA-107 reversed the effects of HOTAIRM1 overexpression.

From: RETRACTED ARTICLE: The HOTAIRM1/miR-107/TDG axis regulates papillary thyroid cancer cell proliferation and invasion

Fig. 5

a Expression levels of miR-107 in HOTAIRM1-overexpressing B-CPAP and TPC-1 cells transfected with miR-NC or miR-107 mimics, assessed by qRT-PCR (n = 3, **p < 0.001). b Micro-RNA-107 mimics reversed the HOTAIRM1-induced inhibition of cell proliferation (n = 3, **p < 0.001). c miRNA-107 mimics reversed the HOTAIRM1-induced cell apoptosis (N = 3, **p < 0.001). d, e miRNA-107 mimics restored the migration and invasion ability impaired by HOTAIRM1 in B-CPAP (D) and TPC-1 (E) cells (n = 3, **p < 0.001). Scale bar: 100 μm. f Migration was evaluated by wound healing assays in B-CPAP and TPC-1 cells stably overexpressing HOTAIRM1 and transfected with miR-NC or miR-107 mimics (n = 3, **p < 0.001).

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