Fig. 7: Immunohistological analysis of CAV1, ASMase, and ceramide expression levels in human PCa tissues. | Cell Death & Disease

Fig. 7: Immunohistological analysis of CAV1, ASMase, and ceramide expression levels in human PCa tissues.

From: Caveolin-1 regulates the ASMase/ceramide-mediated radiation response of endothelial cells in the context of tumor–stroma interactions

Fig. 7

Paraffin sections of human PCas were stained for the indicated antibodies using either IHC (a) or immunofluorescence (b). Gleason grading scores were divided into low (Gleason Score ≥6, Grade group 1), intermediate (Gleason Score 7 (a/b), Grade groups 2 and 3), and high scores (Gleason Score ≥8, Grade groups 4 and 5). Asterisks mark stromal compartments and bold arrows point to epithelial structures. Sections were counterstained using hematoxylin (a, IHC) or DAPI (b, immunoflourescence). Representative images are shown. Magnification ×40 (phase contrast), scale bar: 100 µm; ×63 (immunofluorescence), scale bar: 20 µm.

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