Table 1 Cell viability of alteronol in melanoma cells.

From: Autophagy inhibition potentiates the anti-EMT effects of alteronol through TGF-β/Smad3 signaling in melanoma cells

Cell lines

IC50 (μM)

24 h

48 h

A375

3.72 ± 0.32

2.53 ± 0.43

WM35

5.31 ± 0.21

4.42 ± 0.27

UACC62

4.92 ± 0.60

4.47 ± 0.16

HUVEC

>30

>30

  1. Melanoma cells were treated with increasing concentrations of alteronol for 24 and 48 h, respectively. The cell growth was evaluated by MTT assay. Experiments were performed in triplicate, and the results were presented as the mean ± SD.