Fig. 1: miRNAs were selected by prediction tools and a western blot analysis.

a We selected 14 miRNAs that simultaneously curbed the expression of VEGFR1/2 and NRP1 using a Venn diagram. b The expression of miRNAs was detected in gastric cancer lines (AGS and MKN45) and in a normal gastric mucosal cell line (GES1) by qRT-PCR analysis. c The miRNA expression was significantly increased in the gastric cancer cells after transfection with miRNA mimics. d VEGFR1/2 and NRP1 expression was examined by a western blot in AGS gastric cell lines after transfecting miR-590 mimics and cont-miR. The data are shown as the mean ± s.d. (n = 3) in cell lines *p < 0.05.