Table 1 Harmonic regression analysis parameters.

From: Effect of naive and cancer-educated fibroblasts on colon cancer cell circadian growth rhythm

Cells

Period (h)

Amplitude

Acrophase (h)

p-value

Acrophase shift (h)

Clock

  Naive fibroblasts

18

0.08

32.00

0.0116

2.16

  TAF

30

0.05

30.99

0.3208

1.14

  HCT116

18

0.23

29.85

0.0004

0

  HCT116 naive fibroblasts

18.1

0.68

30.31

0.0000

0.47

  HCT116 TAF

204

0.60

29.03

0.0000

−0.82

Bmal1

  Naive fibroblasts

30

0.10

22.03

0.4269

−7.38

  TAF

30

0.09

39.82

0.0000

10.41

  HCT116

18.2

0.15

29.41

0.0000

0

  HCT116 naive fibroblasts

23

0.48

23.26

0.0133

−6.14

  HCT116 TAF

30

0.21

44.97

0.0001

15.57

Per1

  Naive fibroblasts

30

0.36

23.34

0.0011

−24.80

  TAF

30

0.64

40.61

0.0001

−7.53

  HCT116

30

0.19

48.15

0.0000

0

  HCT116 naive fibroblasts

18

0.27

29.84

0.0000

−18.31

  HCT116 TAF

18

0.22

29.29

0.0451

−18.86

Cry1

  Naive fibroblasts

23.1

0.07

37.63

0.0000

7.47

  TAF

30

0.04

38.18

0.1212

8.02

  HCT116

18

0.46

30.16

0.0003

0

  HCT116 naive fibroblasts

18.1

0.32

30.37

0.0000

0.21

  HCT116 TAF

19

0.23

30.01

0.0000

−0.15

TIM

  Naive fibroblasts

30

0.24

40.17

0.0122

11.32

  TAF

18

0.14

5.48

0.0956

−23.37

  HCT116

18

0.43

28.85

0.0286

0

  HCT116 naive fibroblasts

18

0.46

28.95

0.0000

0.10

  HCT116 TAF

21.9

0.58

28.30

0.0000

−0.55

pERK1/2

  Naive fibroblasts

18

1.59

26.56

0.0116

−7.64

  TAF

18.3

1.59

29.06

0.0042

−5.13

  HCT116

20.3

2.83

34.20

0.0001

0

  HCT116 naive fibroblasts

22.5

3.81

28.00

0.0000

−6.20

  HCT116 TAF

30

2.19

38.04

0.0000

3.84

cMYC

  Naive fibroblasts

30

0.42

22.04

0.0012

−18.34

  TAF

18

0.03

36.03

0.0023

−4.35

  HCT116

30

0.34

40.38

0.0024

0

  HCT116 naive fibroblasts

18

0.36

31.50

0.0007

−8.88

  HCT116 TAF

30

0.44

38.63

0.0004

−1.75

cycD1

  Naive fibroblasts

18

0.10

32.90

0.0081

5.51

  TAF

30

0.11

37.73

0.0003

9.34

  HCT116

25.4

0.08

28.40

0.0001

0

  HCT116 naive fibroblasts

18

0.09

31.23

0.0031

2.83

  HCT116 TAF

22.3

0.14

35.94

0.0030

7.55

CREB

  Naive fibroblasts

30

0.08

35.40

0.0767

1.33

  TAF

30

0.40

39.14

0.0000

5.07

  HCT116

30

0.22

34.07

0.0023

0

  HCT116 naive fibroblasts

24.6

0.15

27.47

0.0000

−6.60

  HCT116 TAF

30

0.14

35.10

0.0227

1.02

  1. Circadian period, amplitude, and acrophase, of naive fibroblasts, TAFs, HCT116 cells, HCT116 cells co-cultured with naive fibroblasts, and HCT116 cells co-cultured with TAFs. Parameters are based on the Western blot band intensities.
Back to article page