Fig. 6: Clinical evidences of miR-4476/APC/β-catenin/c-Jun axis. | Cell Death & Disease

Fig. 6: Clinical evidences of miR-4476/APC/β-catenin/c-Jun axis.

From: MicroRNA-4476 promotes glioma progression through a miR-4476/APC/β-catenin/c-Jun positive feedback loop

Fig. 6: Clinical evidences of miR-4476/APC/β-catenin/c-Jun axis.

a–c Expression levels correlation between 4476 and APC, miR-4476 and c-Jun, APC and c-Jun. c-Jun and APC expression level were scored by IHC staining, and miR-4476 expression levels were detected by in situ hybridization. d Kaplan–Meier survival analysis of overall survival of 87 glioma patients on the basis of miR-4476 expression levels. e, f Kaplan–Meier survival analysis of overall survival of 676 glioma patients on the basis of APC or c-Jun expression levels, using GEPIA website. Mean ± S.D., *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.

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