Fig. 4: MCL-1^Matrix regulates mitochondrial calcium retention capacity.

a, b Calcium retention capacity (CRC) in MCL-1 ∆/- MEFs expressing cherry, MCL-1^OM or MCL-1^Matrix exposed to consecutive pulses of Ca²⁺ (8.5 µM). Experiments were performed in the presence of Succinate (5 mM), Rotenone (1 µM) and Pi (10 mM) (a). Quantification of number of calcium pulses before pore opening (b) (average ± SD from four to five independent experiments). Data information: one-way ANOVA followed by Tukey’s post hoc test.