Fig. 6: HCC could originate from hepatocytes.
From: Oncogenic driver genes and tumor microenvironment determine the type of liver cancer
a IHC showed that some scattered HA-tag strongly positive hepatocytes were detected in AKT-injected livers after 7 days. b IHC results showed that HA-tag protein was also expressed in HCC tumor tissues after 6 months. c HE staining showed that AKT-initiated tumors were characterized by lipid rich droplets. d IHC results showed that PCNA protein was highly expressed in HCC tumor tissues after 6 months. HCC: hepatocellular carcinoma; IHC: immunohistochemical staining; HE: hematoxylin-eosin staining (scale bars, 50 μm).
