Fig. 3: The knockdown of CHPF inhibits MM tumor growth in vivo. | Cell Death & Disease

Fig. 3: The knockdown of CHPF inhibits MM tumor growth in vivo.

From: Chondroitin polymerizing factor (CHPF) promotes development of malignant melanoma through regulation of CDK1

Fig. 3

a The photo of xenograft tumors removed from the mice models in shCtrl and shCHPF groups. b The weight of tumors was measured after the sacrifice of mice models. c The volume of tumors was measured and calculated during experiments. d The mRNA expression of CHPF in tumors was detected by qPCR. e The Ki-67 index of the removed tumors was evaluated by IHC analysis (Magnification ×100). f The Tunel staining of the sectioned tumors was performed to assess the apoptosis rate. The data were expressed as mean ± SD (n ≥ 3), *P < 0.05, **P < 0.01, ***P < 0.001.

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