Fig. 4: miRNA sequencing revealed potential key targets in MSC-derived EVs. | Cell Death & Disease

Fig. 4: miRNA sequencing revealed potential key targets in MSC-derived EVs.

From: Extracellular vesicle-mediated transfer of miR-21-5p from mesenchymal stromal cells to neurons alleviates early brain injury to improve cognitive function via the PTEN/Akt pathway after subarachnoid hemorrhage

Fig. 4

a Non-coding RNA sequencing revealed microRNA is the largest portion. b miRNA maturation analysis indicated that about half miRNA was single-chain mature form. c Total numbers of reads representing the top 25 miRNAs according to miRNA profiling of MSC-derived EVs are shown. d The top 7 miRNAs accounted for 59.6% of the total miRNA in MSC EVs.

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