Fig. 1: SVEP1 expression pattern and its correlation with prognosis in human HCC. | Cell Death & Disease

Fig. 1: SVEP1 expression pattern and its correlation with prognosis in human HCC.

From: The novel miR-1269b-regulated protein SVEP1 induces hepatocellular carcinoma proliferation and metastasis likely through the PI3K/Akt pathway

Fig. 1: SVEP1 expression pattern and its correlation with prognosis in human HCC.

a. Full transcriptome sequencing of two groups of HCC patients with different risk of recurrence; revealed the signaling pathways in which DEGs are enriched. b Heatmap of the top 20 DEGs in these two groups. c IHC and HE staining of SVEP1 in HCC and para-tumor tissues (the images shown are representative, the IHC scores of para-tumor, SVEP1 high expression tumor and SVEP1 low expression tumor are 6, 3, and 1, respectively). d. WB showing the differences in SVEP1 protein levels between four pairs of HCC tissues and para-tumor tissues. e, f. Kaplan–Meier survival curve analysis of the correlation between SVEP1 IHC scores and HCC patient OS and DFS (n = 207).

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