Fig. 2: The relationship between SVEP1 expression and clinicopathological features of HCC. | Cell Death & Disease

Fig. 2: The relationship between SVEP1 expression and clinicopathological features of HCC.

From: The novel miR-1269b-regulated protein SVEP1 induces hepatocellular carcinoma proliferation and metastasis likely through the PI3K/Akt pathway

Fig. 2: The relationship between SVEP1 expression and clinicopathological features of HCC.

a GSEA validating the correlation between SVEP1 expression and the downregulated expression of genes in HCC tissues. b, c. GSE45436 and TCGA validation of the expression of SVEP1 in HCC and para-tumor tissues. d, e Kaplan–Meier survival curve of TCGA data to validate the correlation between the expression of SVEP1 and HCC patient OS and DFSs. f, g. Correlation analysis between the SVEP1 IHC score and clinicopathological parameters (tumor size and satellite nodules). h, i. Kaplan–Meier survival curve showing the correlation between the SVEP1 IHC score and the OS of a subgroup of HCC patients tumor size ≥3 cm and satellite nodule positive patients. j, k Kaplan–Meier survival curve showing the correlation between the SVEP1 IHC score and DFS of a subgroup of HCC patients (tumor size ≥3 cm and satellite nodules positive patients).

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