Cell Death & Disease

Table 1 The ZHX2 expression and clinicopathological characteristics in ccRCC patients.

From: ZHX2 drives cell growth and migration via activating MEK/ERK signal and induces Sunitinib resistance by regulating the autophagy in clear cell Renal Cell Carcinoma

	Patients		Tumoral ZHX2 expression
Characteristics	n	%	Low	High	P-value
All patients	358	100	239	119
Gender					0.548
Male	254	70.9	172	82
Female	104	29.1	67	37
Age(years)					0.970
≤55	178	49.7	119	59
>55	180	50.3	120	60
TNM stage					0.215
I + II	341	95.3	230	111
III + IV	17	4.7	9	8
pT stage					0.436
T1 + T2	344	96.1	231	113
T3 + T4	14	3.9	8	6
pN stage					0.150
N0	349	97.5	235	114
N1	9	2.5	4	5
pM stage					0.080
M0	352	98.3	237	115
M1	6	1.7	2	4
Fuhrman grade					0.004*
I + II	297	83	208	89
III + IV	61	17	31	30
Tumor size(cm)					0.278
≤4	186	52	129	57
>5	172	48	110	62
Metastasis after surgery					0.009*
Yes	74	20.7	40	34
No	284	79.3	199	85

*Means significant difference.

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