Fig. 1: Nestin was consistent with nephrin expression, and negatively correlated with proteinuria in lupus nephritis.
From: Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress
a Expression of nestin protein and synaptopodin in the glomerulus of LN patients was detected by immunofluorescence. Scale bars: 25 μm. b Expression of nestin and nephrin protein in glomerulus of LN patients in different stages was detected by immunohistochemistry. Scale bars: 50 μm. c There was a significantly positive correlation between nestin expression and nephrin expression in LN patients (n = 80 glomeruli). d There was a significantly negative correlation between nestin expression and proteinuria level in LN patients (n = 52 patients). e There was a significantly negative correlation between nephrin expression and proteinuria level in LN patients (n = 52 patients). f Expression of nestin and nephrin protein in glomerulus of MRL/lpr mice was detected by immunohistochemistry. Scale bars: 50 μm. g There was a significantly positive correlation between nestin and nephrin expression in MRL/lpr mice (n = 19 mice). h There was a significantly negative correlation between nestin expression and proteinuria level in MRL/lpr mice (n = 19 mice). i There was a significantly negative correlation between nephrin expression and proteinuria level in MRL/lpr mice (n = 19 mice).
