Fig. 1: NLRP3 inflammasome formation in the hippocampus of EAE mice. | Cell Death & Disease

Fig. 1: NLRP3 inflammasome formation in the hippocampus of EAE mice.

From: Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype

Fig. 1

a Immunohistochemistry for Iba1 in the hippocampus of each group. Field: ×200 200 μm. b Immunofluorescence for ASC (red), Iba1 (green), and DAPI (blue) in the hippocampus of each group. c Western blots and densitometric analysis for NLRP3, ASC, cleaved caspase-1 p10, and IL-18. β-actin was used as an internal control. The data are mean ± SEM, n = 6, *P < 0.05, **P < 0.01, ***P < 0.001.

Back to article page