Fig. 4: Cellular changes of the cochlear lateral wall.
From: Suppressed expression of LDHB promotes age-related hearing loss via aerobic glycolysis
a Cell counts of type II and IV fibrocytes in the lateral wall were reduced significantly in LDHB KO mice (−/−, black circle) at 5 and 10 months compared to WT mice (+/+, white circle). b Detection of apoptosis with the TUNEL assay in the cochlea of the LDHB KO and WT mice. TUNEL-positive apoptotic cells (green color) were significantly enhanced in the KO mice compared to WT mice. Blue shows DAPI staining of the nucleus. Scale bar = 50 μm. *P < 0.05, **P < 0.01, ***P < 0.001 vs. WT with Student’s t-test.
