Fig. 2: IL-8 promotes malignant progression in HNSCC cell lines. | Cell Death & Disease

Fig. 2: IL-8 promotes malignant progression in HNSCC cell lines.

From: The interaction of interleukin-8 and PTEN inactivation promotes the malignant progression of head and neck squamous cell carcinoma via the STAT3 pathway

Fig. 2

a Migration ability of HNSCC cells treated with the indicated IL-8 concentration was detected by a wound healing assay. Scale bar, 100 μm. b, c Transwell assays were performed to determine the migration and invasion ability of cells with different concentrations of IL-8. Scale bar, 250 μm. d Colony formation ability of cells in three groups was determined using a colony-forming assay. e The CCK8 assay was used to detect the proliferation ability of HNSCC cells with different concentrations of IL-8. f E-cadherin, MMP2, MMP9, and vimentin were detected using western blot after 100 ng/ml IL-8 stimulation; *P < 0.05, **P < 0.01.

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