Fig. 3: Circ-0039411 transcription was activated by FOXM1 in LUAD. | Cell Death & Disease

Fig. 3: Circ-0039411 transcription was activated by FOXM1 in LUAD.

From: Circ-MMP2 (circ-0039411) induced by FOXM1 promotes the proliferation and migration of lung adenocarcinoma cells in vitro and in vivo

Fig. 3: Circ-0039411 transcription was activated by FOXM1 in LUAD.The alternative text for this image may have been generated using AI.

a The result of qRT-PCR of circ-0039411 expression in LUAD and normal cells. b qRT-PCR was utilized to test RNA expression in LUAD cells after Act D treatment. c The qRT-PCR detection of RNA expression after LUAD cells were treated with RNase R. d Ring forming diagram of circ-0039411. e AGE (agarose gel electrophoresis) results of PCR products amplified by convergent or divergent primers. f The binding motif of FOXM1 and the two possible FOXM1 binding sites in circ-0039411 promoter. g Luciferase reporter assay was carried out to estimate the impact of FOXM1 on circ-0039411 transcription. h qRT-PCR measured the enrichment of circ-0039411 promoter in ChIP products of FOXM1. *P < 0.05, **P < 0.01.

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