Fig. 2: HOXA5 inhibits cervical cancer cell growth in vitro. | Cell Death & Disease

Fig. 2: HOXA5 inhibits cervical cancer cell growth in vitro.

From: HOXA5 inhibits the proliferation and neoplasia of cervical cancer cells via downregulating the activity of the Wnt/β-catenin pathway and transactivating TP53

Fig. 2

The expression of HOXA5 in human cervical cancer cell lines was detected using immunocytochemistry (a) and western blot (b). Stably transfected HOXA5-modified cervical cancer cell lines were identified by western blotting (c, f, i, l). The proliferation was detected using growth curves in HeLa-GFP and HeLa-HOXA5 cells (d), SiHa-GFP and SiHa-HOXA5 cells (g), C-33A-shCtrl and C-33A-shHOXA5 cells (j), and C-33A-criCtrl and C-33A-cri HOXA5 cells (m). The viability was detected by the MTT assay in HeLa-GFP and HeLa-HOXA5 cells (e), SiHa-GFP and SiHa-HOXA5 cells (h), C-33A-shCtrl and C-33A-shHOXA5 cells (k), and C-33A-criCtrl and C-33A-cri HOXA5 cells (n). Data were statistically analyzed with Student’s t-test and values are shown as the mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001.

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