Fig. 3: HOXA5 inhibits cervical cancer cell growth in vivo. | Cell Death & Disease

Fig. 3: HOXA5 inhibits cervical cancer cell growth in vivo.

From: HOXA5 inhibits the proliferation and neoplasia of cervical cancer cells via downregulating the activity of the Wnt/β-catenin pathway and transactivating TP53

Fig. 3

a Xenograft tumor formation of HeLa-GFP and HeLa-HOXA5 cells. The tumor growth curve (b), tumor weight (c), and tumor-free survival (d) of HeLa-GFP and HeLa-HOXA5 cells, respectively. e Xenograft tumor formation of SiHa-GFP and SiHa-HOXA5 cells. The tumor growth curve (f), tumor weight (g), and tumor-free survival (h) of SiHa-GFP and SiHa-HOXA5 cells, respectively. i Immunohistochemical staining of HOXA5 and Ki67 in xenograft tumor tissues derived from HeLa-GFP cells, HeLa-HOXA5 cells, SiHa-GFP and SiHa-HOXA5 cells, respectively. j Immunoreactivity scores of HOXA5 and Ki-67 in xenograft tumor tissues derived from HeLa-GFP cells, HeLa-HOXA5 cells, SiHa-GFP and SiHa-HOXA5 cells. Data were statistically analyzed with Student’s t-test and values are shown as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001.

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