Fig. 8: Correlation analysis between the expression of HOXA5 with Wnt signaling and p53 in human cervical cancer specimens. | Cell Death & Disease

Fig. 8: Correlation analysis between the expression of HOXA5 with Wnt signaling and p53 in human cervical cancer specimens.

From: HOXA5 inhibits the proliferation and neoplasia of cervical cancer cells via downregulating the activity of the Wnt/β-catenin pathway and transactivating TP53

Fig. 8

a Fifteen cervical cancer specimens were analyzed by IHC, and the representative images of HOXA5, β-catenin, cyclinD1, p53, and p21 were shown. b–e Correlation of the HOXA5 staining with β-catenin (r = 0.5931, p < 0.05), c-Myc (r = 0.5186, p < 0.05), cyclinD1 (r = 0.5428, p < 0.05), TP53 (r = 0. 5309, p < 0.05), P21 (r = 0.6204, p < 0.05). f The proposed mechanism of HOXA5 in cervical cancer cells.

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