Fig. 1: PRR14 is amplified and overexpressed in breast cancer. | Cell Death & Disease

Fig. 1: PRR14 is amplified and overexpressed in breast cancer.

From: Oncogene PRR14 promotes breast cancer through activation of PI3K signal pathway and inhibition of CHEK2 pathway

Fig. 1

a Gene copy number information of Chr16 and PRR14 are taken from UCSC Cancer Browser. b The relationship between PRR14 gene mRNA expression and its copy number variation is analyzed by one-way ANOVA analysis. Mean ± s.d. is presented. c PRR14 expression data in TCGA, detected either by RNAseq or array, are retrieved from UCSC Cancer Browser. The implemented in UCSC Cancer Browser statistical analysis using Student’s t-test and adjusting the false discovery rate using the Benjamini–Hochberg procedure identified statistical significance (P < 0.05) with higher expression of PRR14 in cancer samples. d PRR14 expression in breast cancer molecular subtypes: Normal-like (Normal), LumB, LumA, Her2 and Basal, is shown and compared by one-way ANOVA analysis. Mean ± s.d. is presented. e The genetic information of PRR14 in Breast Invasive Carcinoma in TCGA is profiled.

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