Fig. 3: Apoptotic genes’ expression. | Cell Death & Disease

Fig. 3: Apoptotic genes’ expression.

From: Novel XIAP mutation causing enhanced spontaneous apoptosis and disturbed NOD2 signalling in a patient with atypical adult-onset Crohn’s disease

Fig. 3

a Ratio of pro- and anti-apoptotic genes BAK, BAX and Bcl2 in the patient and control (n = 2) PBMCs after 6 h of stimulation with staurosporine (1 mmol) or PMA (50 ng/ml) as detected by RT-PCR. b Expression of caspase-independent genes involved in apoptosis, AIMF1 and ENDOG, in the patient and control (n = 2) PBMCs after 6 h of stimulation with staurosporine (1 mmol) or PMA (50 ng/ml) as detected by RT-PCR. c Expression of the BIRC2 gene in control (n = 2) PBMCs as detected by RT-PCR. Gene expression was normalized to that of GAPDH.

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