Fig. 1: PIM2 is frequently upregulated in HCC patients. | Cell Death & Disease

Fig. 1: PIM2 is frequently upregulated in HCC patients.

From: PIM2 promotes hepatocellular carcinoma tumorigenesis and progression through activating NF-κB signaling pathway

Fig. 1

a Relative expression of PIM2 in 134 pairs of paired HCC tumor and nontumor tissues detected by qRT-PCR. b Ratio of PIM2’s relative expression level between paired HCC tumor and nontumor tissue. Upregulation or downregulation are defined as more than twofold change. c Representative image of IHC staining of PIM2’s expression in paired HCC tumor and nontumor tissue. Original magnification, ×400. d Expression of PIM2 in HCC cell lines detected by Western Blot. e Kaplan–Meier overall survival curve and f disease-free survival curve of HCC patients correlated with the expression of PIM2. PIM2 (+), patients with PIM2 upregulation; PIM2 (−), patients without PIM2 upregulation.

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