Fig. 3: Effect of FOXA2 haploinsufficiency on pancreatic endocrine progenitors (EPs) differentiation.
From: Aberrant development of pancreatic beta cells derived from human iPSCs with FOXA2 deficiency
A Representative immunofluorescent images showing the expression of FOXA2, NGN3, CHGA, NEUROD1, and NKX6.1 in endocrine progenitors (EPs) derived from Ctr-iPSCs and FOXA2+/− iPSCs. B Real-time PCR analysis for the expression of the key EPs markers, FOXA2, NGN3, CHGA, NEUROD1, NKX6.1, and NKX2.2 in the EPs derived from Ctr-iPSCs and FOXA2+/− iPSCs. Data are represented as mean ± SD; *p < 0.05, **p < 0.01, ***p < 0.001.
