Fig. 7: FAP cell states from wild type mice differ in their transcriptional profile.
From: SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors
a viSNE map representing the different clusters identified as distinct cell populations according to the expression of specific biomarkers. Identified populations are: myocytes, B-cells, FAPs, smooth muscle cells, MuSCs, endothelial cells, macrophages, T-cells, tenocytes and neurons. b The FAPs population subset has been re-clustered, leading to 4 distinct clusters according to their gene expression profile. The four clusters (0, 1, 2,3) were mapped onto the viSNE map of FAPs. c The expression of SCA-1 antigen has been mapped to each cell of the dataset. d viSNE map of FAPs in which clusters 0, 2, 3 are collapsed together to obtain two clusters expressing high level (SCA-1 High) and low level (SCA-1 Low) of SCA-1. e Stacked bar plot showing the percentage of the two population on the basis of SCA-1 expression levels across different ages.
