Fig. 1: Glucose challenge induced vascular constriction in humans and mice. | Cell Death & Disease

Fig. 1: Glucose challenge induced vascular constriction in humans and mice.

From: Acute glucose influx-induced mitochondrial hyperpolarization inactivates myosin phosphatase as a novel mechanism of vascular smooth muscle contraction

Fig. 1

A–F Blood glucose (A), systolic blood pressure (SBP) (B) and the maximal brachial artery diameter (C) in response to oral glucose challenge in humans. Representative images of the maximal diameter of brachial artery in response to glucose challenge are shown in left, and the quantified results are shown in right (C). n = 8 subjects. D–F Blood glucose (D), SBP (E), and the maximal abdominal aorta diameter (F) in response to intraperitoneal glucose challenge in mice. Representative images of the maximal abdominal aorta in response to glucose challenge are shown in left, and the quantified results are shown in right (F). n = 8 mice. Error bars represent SEM. *P < 0.05. **P < 0.01.

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