Fig. 4: Differing treatment methods deserve consideration for the application of BH3 mimetics in combination with standard therapies. | Cell Death & Disease

Fig. 4: Differing treatment methods deserve consideration for the application of BH3 mimetics in combination with standard therapies.

From: The application of BH3 mimetics in myeloid leukemias

Fig. 4

Proposed methods for combination treatments with BH3 mimetics include co-treatment with a chemotherapy or inducing an increase in dependency on a BCL-2 prosurvival protein by treatment with chemotherapy which can then be targeted with a BH3 mimetic (one-two punch method).

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