Fig. 6: 3-MA potentiates apoptosis induced by inhibition of autophagy. | Cell Death & Disease

Fig. 6: 3-MA potentiates apoptosis induced by inhibition of autophagy.

From: Suppression of steroid 5α-reductase type I promotes cellular apoptosis and autophagy via PI3K/Akt/mTOR pathway in multiple myeloma

Fig. 6: 3-MA potentiates apoptosis induced by inhibition of autophagy.

A Effect of 3-MA and/or Dox on the growth of ARP1 and H929-SRD5A1-KD cells measured by MTT assay. B Western blotting analysis of SQSTM1, caspase-3, cleaved caspase-3 and PARP, cleaved PARP in response to 3-MA and/or Dox treatment in ARP1- and H929-SRD5A1-KD cells. *P < 0.05, **P < 0.01, ***P < 0.001.

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