Fig. 1: Electron microscopy images of SARS-CoV-2 virus and infected Vero cells.
From: Evidences for lipid involvement in SARS-CoV-2 cytopathogenesis
A Negative staining electron microscopy micrographs of SARS-CoV-2 particle. The virion display a spherical shape, on the surface cone-like shaped spikes are visible (white arrow). B–D Infected cells show numerous viruses associated to the plasma membrane (arrowheads) especially found along microvillous projections (arrows). Many lipid droplets (LD) and lipolysosomes (LL) are visible (D). E A great number of vacuoles are present in the cell cytoplasm, many of which contain viral particles (arrows). F Other vesicles, small in size, contain single viral particles, resembled the “spherules” described for other coronaviruses (arrows). Viruses are visible along the plasma membrane (arrowheads). Numerous free ribosomes are diffused in the cell cytosol. N nucleus, m mitochondria, LD lipid droplets, LL lipolysosomes. Scale bars: A = 100 nm; B, D, F = 1 μm; C, E = 200 nm.
