Fig. 5: FcγR dependency of iIC-induced neutrophil apoptosis and iIC internalization. | Cell Death & Disease

Fig. 5: FcγR dependency of iIC-induced neutrophil apoptosis and iIC internalization.

From: Immune complex-induced apoptosis and concurrent immune complex clearance are anti-inflammatory neutrophil functions

Fig. 5

A Following incubation on ice with FcγR blocking antibodies (3G8, IV.3) or vehicle as indicated neutrophils were stimulated with 10 μg/ml iICs for analysis of neutrophil apoptosis after 12 h. Internalization of beads (B) and iICs (C) by neutrophils that had been incubated with blocking antibodies (3G8, AT10) or vehicle as indicated. Each symbol represents the average value obtained in a separate experiment. Data were subjected to analysis by one-way ANOVA with multiple comparisons post-hoc test; *p < 0.05; **p < 0.01; ***p < 0.001.

Back to article page