Fig. 4: KO-miR-127-3p relieved autophagy in vitro.
From: MiR-127-3p targeting CISD1 regulates autophagy in hypoxic–ischemic cortex
A Autophagy of neurons was increased significantly in OGD, and reduced significantly in miR-127-3p inhibitor. B, C–G The relative expression of ATG12, Beclin-1, P62, and LC 3II was obviously increased, and the relative expression of LC 3I was decreased significantly. However, the expression result of ATG12, Beclin-1, P62, LC3I, and LC3II was opposite in the miR127 KO rat group. OGD oxygen glucose deprivation, KO knock out. Scale bar = 20 μm. The data are presented as the means ± s.d. **P < 0.01 with one-way ANOVA, n = 6.
