Fig. 3: GSCs with pH 6.8 treatment have high rates of de novo purine nucleotide biosynthesis utilizing glucose-derived carbon.
From: Rewiring of purine metabolism in response to acidosis stress in glioma stem cells

a A schematic illustrating the metabolic assimilation of glucose-carbon to nucleotide biosynthesis. b–d Fraction (%) of purine and pyrimidine metabolites in GSC2 cultured at pH 6.8 and pH 7.4.