Fig. 1: Effects of upregulation of miR-21-5p on renal function and pathological changes in the kidney of CLP rats.

A Comparison of Scr concentration in CLP rats. B Comparison of BUN concentration in CLP rats. C HE staining of rat renal tissues (scale bar = 50 μm). D Comparison of renal tubular injury scores in CLP rats. E PAS staining of rat renal tissues of CLP rats (scale bar = 50 μm). F Comparison of the number of renal tubular injuries of CLP rats. n = 10. *P < 0.05 vs. the sham group. #P < 0.05 vs. the Ago-NC group. &P < 0.05 vs. the Ago-miR-21-5p + Oe-NC group. Measurement data were depicted as mean ± standard deviation.