Fig. 1: Design and purity of V-aCD3. | Cell Death & Disease

Fig. 1: Design and purity of V-aCD3.

From: Development of a bispecific immune engager using a recombinant malaria protein

Fig. 1: Design and purity of V-aCD3.

A Schematic figure of the construction and assembly of V-aCD3. A single-chain anti-CD3 antibody (scFv (OKT3)-Fc (murine IgG2b)) was produced with a SpyCatcher domain, which spontaneously forms a covalent bond with SpyTagged VAR2. B SDS-PAGE showing recombinant rVAR2 (lane 2 nonreduced, lane 3 reduced), V-aCD3 (lane 4 nonreduced, lane 5 denatured), and anti-CD3 (lane 6 nonreduced, lane 7 reduced).

Back to article page