Fig. 4: Intracellular Kv1.3 channels regulate proliferation and respiration. | Cell Death & Disease

Fig. 4: Intracellular Kv1.3 channels regulate proliferation and respiration.

From: Kv1.3 voltage-gated potassium channels link cellular respiration to proliferation through a non-conducting mechanism

Fig. 4: Intracellular Kv1.3 channels regulate proliferation and respiration.

A Proliferation assay of HEK293/Kv1.3 cells treated with PAPTP (100 nM; n = 5). B Residual O2 consumption (ROX) corrected Routine, Leak and maximal ETS respiration in HEK293/Kv1.3 cells treated with PAPTP (100 nM; n = 5). C ATP turnover in HEK293/Kv1.3 cells treated with PAPTP (100 nM; n = 5). D Spare respiratory capacity in HEK293/Kv1.3 cells treated with PAPTP (100 nM; n = 5). Data were mean ± SEM. Data were analysed using a paired Student’s t-test. *p < 0.05 and ***p < 0.001.

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