Fig. 2: Visual function impairment in homozygous Adipor1 KO mice. | Cell Death & Disease

Fig. 2: Visual function impairment in homozygous Adipor1 KO mice.

From: ADIPOR1 deficiency-induced suppression of retinal ELOVL2 and docosahexaenoic acid levels during photoreceptor degeneration and visual loss

Fig. 2

Full-field scotopic ERGs at 3 (A, B), and 10 weeks of age (C, D). Representative waveform from individual mice at each stimulus intensity (A, C). The a-wave amplitudes decreased in homozygous KO mice compared to WT and heterozygous mice at 3 and 10 weeks. The reduction in amplitudes and increased implicit time of the b-wave became evident at 10 weeks. No differences were observed between WT and heterozygotes. Data are shown as means ± standard deviations. n = 5, **P < 0.01 vs. WT, one-way ANOVA.

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