Fig. 1: Improvement of cardiac function at 8 weeks after TAC by genetic deletion of RAGE or an autophagy inhibitor (3-MA or CQ).

A Representative M-mode images. Echocardiography was performed to measure LVEF (B), LVFS (C), LVIDd (D), LVIDs (E), LVEDV (F), and LVESV (G). n = 8. Data are presented as mean ± SEM. *p < 0.05 vs. sham group, #p < 0.05 vs. TAC group.